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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621400
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:39348
Term: etofenprox
Definition: An aromatic ether that is the 3-phenoxybenzyl ether of 2-(4-ethoxyphenyl)-2-methylpropan-1-ol.
Chemical ID: MESH:C076840
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3multiple interactionsEXP 6480464CTD[ethofenprox co-treated with Diethylnitrosamine] results in decreased expression of NR1I3 mRNA ethofenprox affects the localization of and results in increased activity of NR1I3 protein

PMID:22467020
Nr1i3increases activityISORGD:13441636480464CTDethofenprox results in increased activity of NR1I3 protein

PMID:28927721
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