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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735336
Species: Mus musculus
RGD Object: Gene
Symbol: Akt1
Name: thymoma viral proto-oncogene 1
Acc ID: CHEBI:39329
Term: etoxazole
Definition: An organofluorine acaricide that has formula C21H23F2NO2.
Chemical ID: MESH:C508136
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akt1increases phosphorylationEXP 6480464CTDetoxazole results in increased phosphorylation of AKT1 proteinPMID:33618463
Akt1multiple interactionsEXP 6480464CTD2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [etoxazole results in increased phosphorylation of AKT1 protein]; pyrazolanthrone inhibits the reaction [etoxazole results in increased phosphorylation of AKT1 protein]; U 0126 promotes the reaction [etoxazole results in increased phosphorylation of AKT1 protein]PMID:33618463
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