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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 13887126
Species: Sus scrofa
RGD Object: Gene
Symbol: MAPK3
Name: mitogen-activated protein kinase 3
Acc ID: CHEBI:39329
Term: etoxazole
Definition: An organofluorine acaricide that has formula C21H23F2NO2.
Chemical ID: MESH:C508136
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MAPK3increases phosphorylationEXP 6480464CTDetoxazole results in increased phosphorylation of MAPK3 proteinPMID:31744678
MAPK3multiple interactionsEXP 6480464CTD[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; [pyrazolanthrone co-treated with etoxazole] results in increased phosphorylation of MAPK3 protein; SB 203580 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [etoxazole results in increased phosphorylation of MAPK3 protein]PMID:31744678
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