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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730823
Species: Homo sapiens
RGD Object: Gene
Symbol: ABCB1
Name: ATP binding cassette subfamily B member 1
Acc ID: CHEBI:39230
Term: emamectin
Definition: A mixture of emamectin B1a (major component) and emamectin B1b (minor component).
Chemical ID: MESH:C443359
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ABCB1decreases activityEXP 6480464CTDemamectin results in decreased activity of ABCB1 proteinPMID:25865432
ABCB1multiple interactionsEXP 6480464CTDemamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]PMID:25865432
ABCB1decreases activityISOAbcb1a (Mus musculus)6480464CTDemamectin results in decreased activity of ABCB1A proteinPMID:25865432
ABCB1multiple interactionsISOAbcb1a (Mus musculus)6480464CTDemamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]PMID:25865432
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