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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcb1a
Name: ATP binding cassette subfamily B member 1A
Acc ID: CHEBI:39230
Term: emamectin
Definition: A mixture of emamectin B1a (major component) and emamectin B1b (minor component).
Chemical ID: MESH:C443359
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcb1adecreases activityISORGD:16208906480464CTDemamectin results in decreased activity of ABCB1A protein

PMID:25865432
Abcb1adecreases activityISORGD:7308236480464CTDemamectin results in decreased activity of ABCB1 protein

PMID:25865432
Abcb1amultiple interactionsISORGD:16208906480464CTDemamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]

PMID:25865432
Abcb1amultiple interactionsISORGD:7308236480464CTDemamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]

PMID:25865432
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