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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3112
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc1
Name: ATP binding cassette subfamily C member 1
Acc ID: CHEBI:39230
Term: emamectin
Definition: A mixture of emamectin B1a (major component) and emamectin B1b (minor component).
Chemical ID: MESH:C443359
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc1decreases activityISORGD:109196480464CTDemamectin results in decreased activity of ABCC1 protein

PMID:25865432
Abcc1decreases activityISORGD:13446246480464CTDemamectin results in decreased activity of ABCC1 protein

PMID:25865432
Abcc1multiple interactionsISORGD:109196480464CTDemamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]

PMID:25865432
Abcc1multiple interactionsISORGD:13446246480464CTDemamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]

PMID:25865432
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.