Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	736485
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Sqstm1
Name:	sequestosome 1

Acc ID:	CHEBI:39214
Term:	abamectin
Definition:	Mixture of 80% avermectin B1a and 20% avermectin B1b.
Chemical ID:	MESH:C048324

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Sqstm1	decreases expression	ISO	SQSTM1 (Homo sapiens)	6480464	CTD	abamectin results in decreased expression of SQSTM1 protein	PMID:30958899

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.