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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:39214
Term: abamectin
Definition: Mixture of 80% avermectin B1a and 20% avermectin B1b.
Chemical ID: MESH:C048324
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXincreases expressionISOBax (Rattus norvegicus)6480464CTDabamectin results in increased expression of BAX mRNA; abamectin results in increased expression of BAX proteinPMID:34748272
BAXmultiple interactionsISOBax (Rattus norvegicus)6480464CTDHesperidin inhibits the reaction [abamectin results in increased expression of BAX mRNA]; Hesperidin inhibits the reaction [abamectin results in increased expression of BAX protein]PMID:34748272
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