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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3185
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nos2
Name: nitric oxide synthase 2
Acc ID: CHEBI:39186
Term: (E)-thiamethoxam
Definition: A thiamethoxam that has formula C8H10ClN5O3S.
Chemical ID: MESH:C416660
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nos2decreases activityISORGD:109966480464CTDThiamethoxam metabolite results in decreased activity of NOS2 protein

PMID:29197058
Nos2multiple interactionsISORGD:109966480464CTD[Thiamethoxam metabolite results in decreased activity of NOS2 protein] which results in increased chemical synthesis of Formaldehyde

PMID:29197058
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