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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2350
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chrnb2
Name: cholinergic receptor nicotinic beta 2 subunit
Acc ID: CHEBI:39178
Term: clothianidin
Definition: An N-nitro compound consisting of 2-nitroguanidine having a (2-chloro-1,3-thiazol-5-yl)methyl group at position 1 and a methyl group at position 3.
Chemical ID: MESH:C480342
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chrnb2multiple interactionsEXP 6480464CTDclothianidin results in increased activity of [NACHRA1 protein co-treated with CHRNB2 protein] clothianidin results in increased activity of [NACHRA8 protein co-treated with CHRNB2 protein]

PMID:16981889 PMID:25459289
Chrnb2multiple interactionsISORGD:7332186480464CTDclothianidin promotes the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]]

PMID:21538459
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