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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:38957
Term: 4,4'-thiodiphenol
Definition: A phenol that has formula C12H10O2S.
Chemical ID: MESH:C586730
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1increases phosphorylationISORGD:7325026480464CTD4 4'-thiodiphenol results in increased phosphorylation of MAPK1 protein

PMID:27880919
Mapk1multiple interactionsISORGD:7325026480464CTD4-6-bromo-1 3-benzodioxol-5-yl-3a 4 5 9b-3H-cyclopentacquinoline inhibits the reaction [4 4'-thiodiphenol results in increased phosphorylation of MAPK1 protein] fulvestrant inhibits the reaction [4 4'-thiodiphenol results in increased phosphorylation of MAPK1 protein] U 0126 inhibits the reaction [4 4'-thiodiphenol results in increased phosphorylation of MAPK1 protein] wortmannin inhibits the reaction [4 4'-thiodiphenol results in increased phosphorylation of MAPK1 protein]

PMID:27880919
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