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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708363
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp4f4
Name: cytochrome P450, family 4, subfamily f, polypeptide 4
Acc ID: CHEBI:38940
Term: sunitinib
Definition: A pyrrole that has formula C22H27FN4O2.
Chemical ID: MESH:C473478
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp4f4increases expression EXP 401793741RGDsunitinib increases expression of mRNA in rat cardiomyocytes 
Cyp4f4increases expressionEXP 6480464CTDsunitinib results in increased expression of CYP4F4 mRNAPMID:24247421 PMID:26797788
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