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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1348437
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP9
Name: matrix metallopeptidase 9
Acc ID: CHEBI:38940
Term: sunitinib
Definition: A pyrrole that has formula C22H27FN4O2.
Chemical ID: MESH:C473478
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP9decreases expressionISOMmp9 (Rattus norvegicus)6480464CTDsunitinib results in decreased expression of MMP9 mRNAPMID:26581635
MMP9multiple interactionsISOMmp9 (Rattus norvegicus)6480464CTDCarnitine inhibits the reaction [sunitinib results in decreased expression of MMP9 mRNA]; SN50 peptide inhibits the reaction [sunitinib results in decreased expression of MMP9 mRNA]PMID:26581635
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