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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10439
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:38940
Term: sunitinib
Definition: A pyrrole that has formula C22H27FN4O2.
Chemical ID: MESH:C473478
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1decreases expressionISOCYP1B1 (Homo sapiens)6480464CTDSunitinib results in decreased expression of CYP1B1 mRNAPMID:31533062
Cyp1b1increases expressionISOCyp1b1 (Rattus norvegicus)6480464CTDsunitinib results in increased expression of CYP1B1 mRNAPMID:26797788
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