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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2275
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:38912
Term: Ro 31-8220
Definition: An imidothiocarbamic ester that has formula C25H23N5O2S.
Chemical ID: MESH:C064758
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3multiple interactionsEXP 6480464CTDRo 31-8220 inhibits the reaction [Hexachlorocyclohexane results in increased activity of CASP3 protein] Ro 31-8220 inhibits the reaction [Paraoxon results in increased activity of CASP3 protein]

PMID:17561261 PMID:22001173
Casp3increases activityISORGD:7310026480464CTDRo 31-8220 results in increased activity of CASP3 protein

PMID:18054255
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