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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1349272
Species: Homo sapiens
RGD Object: Gene
Symbol: PON1
Name: paraoxonase 1
Acc ID: CHEBI:38746
Term: parathion-methyl
Definition: A C-nitro compound that is 4-nitrophenol substituted by a (dimethoxyphosphorothioyl)oxy group at position 4.
Chemical ID: MESH:D008743
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PON1decreases expressionEXP 6480464CTDMethyl Parathion results in decreased expression of PON1 mRNAPMID:26948828
PON1multiple interactionsEXP 6480464CTDMethyl Parathion results in decreased expression of and results in decreased activity of PON1 proteinPMID:26948828
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