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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734431
Species: Homo sapiens
RGD Object: Gene
Symbol: NFE2L2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:38728
Term: monocrotophos
Definition: An alkenyl phosphate that is the 4-(methylamino)-4-oxobut-2-en-2-yl ester of dimethyl phosphate.
Chemical ID: MESH:D008999
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NFE2L2increases expressionEXP 6480464CTDMonocrotophos results in increased expression of NFE2L2 proteinPMID:28887667
NFE2L2multiple interactionsEXP 6480464CTDMonocrotophos promotes the reaction [AIFM1 protein binds to NFE2L2 protein]PMID:33078895
NFE2L2decreases expressionISONfe2l2 (Rattus norvegicus)6480464CTDMonocrotophos results in decreased expression of NFE2L2 mRNAPMID:35403558
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