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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346266
Species: Homo sapiens
RGD Object: Gene
Symbol: FAS
Name: Fas cell surface death receptor
Acc ID: CHEBI:38683
Term: 4-nitro-m-cresol
Definition: A C-nitro compound in which the nitro group is attached at C-4 of m-cresol.
Chemical ID: MESH:C008636
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FASincreases expressionEXP 6480464CTD4-nitro-3-cresol results in increased expression of FAS mRNA; 4-nitro-3-cresol results in increased expression of FAS proteinPMID:29307546
FASmultiple interactionsEXP 6480464CTDCASP3 protein promotes the reaction [4-nitro-3-cresol results in increased expression of FAS mRNA]; CASP3 protein promotes the reaction [4-nitro-3-cresol results in increased expression of FAS protein]; CASP8 protein promotes the reaction [4-nitro-3-cresol results in increased expression of FAS mRNA]; CASP8 protein promotes the reaction [4-nitro-3-cresol results in increased expression of FAS protein]PMID:29307546
FASincreases expressionISOFas (Mus musculus)6480464CTD4-nitro-3-cresol results in increased expression of FAS mRNA; 4-nitro-3-cresol results in increased expression of FAS proteinPMID:29307546
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