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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3767
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sult1a1
Name: sulfotransferase family 1A member 1
Acc ID: CHEBI:38472
Term: acetonitrile
Definition: A nitrile that is hydrogen cyanide in which the hydrogen has been replaced by a methyl group.
Chemical ID: MESH:C032159
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sult1a1decreases activityISOSULT1A1 (Homo sapiens)6480464CTDacetonitrile results in decreased activity of SULT1A1 proteinPMID:14570759
Sult1a1multiple interactionsISOSULT1A1 (Homo sapiens)6480464CTDacetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 1-hydroxypyrene]; acetonitrile inhibits the reaction [SULT1A1 protein results in increased sulfation of 4-nitrophenol]PMID:14570759
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