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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 67390
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Orm1
Name: orosomucoid 1
Acc ID: CHEBI:38358
Term: (2E,4E)-hexa-2,4-dienoic acid
Definition: A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.
Chemical ID: MESH:D013011
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Orm1increases expressionISORGD:13321596480464CTDSorbic Acid results in increased expression of ORM1 proteinPMID:20025956
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