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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2627
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fosl1
Name: FOS like 1, AP-1 transcription factor subunit
Acc ID: CHEBI:38358
Term: (2E,4E)-hexa-2,4-dienoic acid
Definition: A sorbic acid having trans-double bonds at positions 2 and 4; a food preservative that can induce cutaneous vasodilation and stinging upon topical application to humans. It is the most thermodynamically stable of the four possible geometric isomers possible, as well as the one with the highest antimicrobial activity.
Chemical ID: MESH:D013011
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosl1increases expressionISORGD:105976480464CTDSorbic Acid results in increased expression of FOSL1 protein

PMID:20025956
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