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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1313985
Species: Mus musculus
RGD Object: Gene
Symbol: Pxn
Name: paxillin
Acc ID: CHEBI:38322
Term: oxotremorine M
Definition: A quaternary ammonium ion that has formula C11H19N2O.
Chemical ID: MESH:C042743
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pxnincreases phosphorylationISORGD:13139846480464CTDoxotremorine M results in increased phosphorylation of PXN protein

PMID:10537051
Pxnmultiple interactionsISORGD:13139846480464CTD[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein] Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] wortmannin inhibits the reaction [oxotremorine M results in increased phosphorylation of PXN protein]

PMID:10537051
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