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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311996
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccl21
Name: C-C motif chemokine ligand 21
Acc ID: CHEBI:38319
Term: usnic acid
Definition: A member of the class of dibenzofurans that is dibenzo[b,d]furan-1(9bH)-one substituted by acetyl groups at positions 2 and 6, hydroxy groups at positions 3 and 7 and methyl groups at positions 8 and 9b.
Chemical ID: MESH:C073339
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl21increases expressionISORGD:13237456480464CTDusnic acid results in increased expression of CCL21 mRNA

PMID:21953288, PMID:22777745
Ccl21multiple interactionsISORGD:13237456480464CTD[usnic acid co-treated with Lipopolysaccharides] results in increased expression of CCL21 mRNA

PMID:22777745
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.