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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621720
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpt
Name: glutamic--pyruvic transaminase
Acc ID: CHEBI:3829
Term: Columbin
Definition: An organic heterotricyclic compound that has formula C20H22O6.
Chemical ID: MESH:C062514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gptincreases activityISORGD:7341926480464CTDcolumbin results in increased activity of GPT protein

PMID:32162908
Gptmultiple interactionsISORGD:7341926480464CTDKetoconazole inhibits the reaction [columbin results in increased activity of GPT protein]

PMID:32162908
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.