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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10436
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a1
Name: cytochrome P450, family 1, subfamily a, polypeptide 1
Acc ID: CHEBI:38265
Term: carvone
Definition: A p-menthane monoterpenoid that consists of cyclohex-2-enone having methyl and isopropenyl substituents at positions 2 and 5, respectively.
Chemical ID: MESH:C006923
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a1increases expressionISOCYP1A1 (Homo sapiens)6480464CTDcarvone results in increased expression of CYP1A1 mRNAPMID:29191726
Cyp1a1multiple interactionsISOCYP1A1 (Homo sapiens)6480464CTDcarvone inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]PMID:29191726
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