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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620349
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptgs2
Name: prostaglandin-endoperoxide synthase 2
Acc ID: CHEBI:38211
Term: potassium bromate
Definition: A bromate salt that has formula BrKO3.
Chemical ID: MESH:C019536
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptgs2increases expressionISOPtgs2 (Mus musculus)6480464CTDpotassium bromate results in increased expression of PTGS2 mRNAPMID:26296324
Ptgs2multiple interactionsISOPtgs2 (Mus musculus)6480464CTD[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA; [XRCC6 gene mutant form results in increased susceptibility to potassium bromate] affects the reaction [[potassium bromate co-treated with bisphenol A] affects the expression of PTGS2 mRNA]; vanillin inhibits the reaction [potassium bromate results in increased expression of PTGS2 mRNA]PMID:26296324 PMID:27082013
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