Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1309681
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Npas2
Name:	neuronal PAS domain protein 2

Acc ID:	CHEBI:38178
Term:	strophanthidin
Definition:	A cardenolide that has formula C23H32O6.
Chemical ID:	MESH:D013327

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Npas2	increases expression	ISO	RGD:1320157	6480464	CTD	Strophanthidin results in increased expression of NPAS2 mRNA	PMID:29981919
Npas2	multiple interactions	ISO	RGD:1320157	6480464	CTD	Strophanthidin promotes the reaction [RORC protein binds to NPAS2 promoter]	PMID:29981919

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