Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736649
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP8B1
Name: cytochrome P450 family 8 subfamily B member 1
Acc ID: CHEBI:38167
Term: physcion
Definition: A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources.
Chemical ID: MESH:C008905
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP8B1decreases expressionISOCyp8b1 (Rattus norvegicus)6480464CTDphyscione results in decreased expression of CYP8B1 mRNA; physcione results in decreased expression of CYP8B1 proteinPMID:28161596
Go Back to source page   Continue to Ontology report