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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bax
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:38167
Term: physcion
Definition: A dihydroxyanthraquinone that is 9,10-anthraquinone bearing hydroxy substituents at positions 1 and 8, a methoxy group at position 3, and a methyl group at position 6. It has been widely isolated and characterised from both terrestrial and marine sources.
Chemical ID: MESH:C008905
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Baxdecreases expressionISORGD:703736480464CTDphyscione results in decreased expression of BAX protein

PMID:22285236
Baxincreases expressionISORGD:703736480464CTDphyscione results in increased expression of BAX protein

PMID:22285236
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.