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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735711
Species: Homo sapiens
RGD Object: Gene
Symbol: CYP1A2
Name: cytochrome P450 family 1 subfamily A member 2
Acc ID: CHEBI:38102
Term: triazines
Definition: Compounds based on a triazine skeleton.
Chemical ID: MESH:D014227
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CYP1A2increases metabolic processingEXP 6480464CTDCYP1A2 protein results in increased metabolism of TriazinesPMID:9305587
CYP1A2multiple interactionsEXP 6480464CTDalpha-naphthoflavone inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]; furafylline inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]; Gestodene inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]; Ketoconazole inhibits the reaction [CYP1A2 protein results in increased metabolism of Triazines]PMID:9305587
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