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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735683
Species: Homo sapiens
RGD Object: Gene
Symbol: SLC31A1
Name: solute carrier family 31 member 1
Acc ID: CHEBI:379896
Term: 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one
Definition: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Chemical ID: MESH:D015741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SLC31A1increases expressionEXP 6480464CTDMetribolone results in increased expression of SLC31A1 mRNA; Metribolone results in increased expression of SLC31A1 proteinPMID:25320179
SLC31A1multiple interactionsEXP 6480464CTD[Metribolone results in increased expression of SLC31A1 protein] which results in increased import of Copper; AR protein promotes the reaction [Metribolone results in increased expression of SLC31A1 mRNA]; AR protein promotes the reaction [Metribolone results in increased expression of SLC31A1 protein]PMID:25320179
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