Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62028
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr0b1
Name: nuclear receptor subfamily 0, group B, member 1
Acc ID: CHEBI:379896
Term: 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one
Definition: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Chemical ID: MESH:D015741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr0b1multiple interactionsISONR0B1 (Homo sapiens)6480464CTD[Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to NR0B1 protein modified form]PMID:28751236
Go Back to source page   Continue to Ontology report