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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1602231
Species: Homo sapiens
RGD Object: Gene
Symbol: ACSL3
Name: acyl-CoA synthetase long chain family member 3
Acc ID: CHEBI:379896
Term: 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one
Definition: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Chemical ID: MESH:D015741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACSL3increases expressionEXP 6480464CTDMetribolone results in increased expression of ACSL3 mRNAPMID:16751804 PMID:17010675
ACSL3multiple interactionsEXP 6480464CTDMetribolone promotes the reaction [NDRG1 protein binds to ACSL3 protein]PMID:17220478
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