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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1559552
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Med1
Name: mediator complex subunit 1
Acc ID: CHEBI:379896
Term: 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one
Definition: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Chemical ID: MESH:D015741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Med1multiple interactionsISOMED1 (Homo sapiens)6480464CTD[Metribolone binds to and affects the folding of AR protein] promotes the reaction [AR protein modified form binds to MED1 protein modified form]PMID:28751236
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