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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1317925
Species: Mus musculus
RGD Object: Gene
Symbol: Pmepa1
Name: prostate transmembrane protein, androgen induced 1
Acc ID: CHEBI:379896
Term: 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one
Definition: A synthetic non-aromatisable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Chemical ID: MESH:D015741
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pmepa1affects expressionISOPMEPA1 (Homo sapiens)6480464CTDMetribolone affects the expression of PMEPA1 mRNAPMID:12711008
Pmepa1increases expressionISOPMEPA1 (Homo sapiens)6480464CTDMetribolone results in increased expression of PMEPA1 mRNAPMID:17010196 PMID:17010675
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