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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3443
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ptk2
Name: protein tyrosine kinase 2
Acc ID: CHEBI:37699
Term: protein kinase inhibitor
Definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Chemical ID: MESH:D047428
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ptk2decreases activityISOPtk2 (Mus musculus)6480464CTDProtein Kinase Inhibitors results in decreased activity of PTK2 proteinPMID:30098273
Ptk2multiple interactionsISOPtk2 (Mus musculus)6480464CTD[Protein Kinase Inhibitors results in decreased activity of PTK2 protein] inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]PMID:30098273
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