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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2886
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il10
Name: interleukin 10
Acc ID: CHEBI:37699
Term: protein kinase inhibitor
Definition: An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases.
Chemical ID: MESH:D047428
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il10decreases secretionISOIl10 (Mus musculus)6480464CTDProtein Kinase Inhibitors results in decreased secretion of IL10 proteinPMID:28003376
Il10multiple interactionsISOIL10 (Homo sapiens)6480464CTDProtein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of IL10 mRNA]PMID:28003376
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