GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bax | increases expression | ISO | BAX (Homo sapiens) | 6480464 | CTD | Oleanolic Acid analog results in increased expression of BAX protein; Oleanolic Acid results in increased expression of BAX protein | PMID:26612655 PMID:34364837 | Bax | multiple interactions | ISO | BAX (Homo sapiens) | 6480464 | CTD | [Oleanolic Acid analog binds to Succinic Acid] which results in increased expression of BAX mRNA; [Oleanolic Acid analog binds to Succinic Acid] which results in increased expression of BAX protein; [Oleanolic Acid results in increased susceptibility to Doxorubicin] which affects the expression of BAX mRNA; Oleanolic Acid inhibits the reaction [ochratoxin A results in increased expression of BAX protein]; TRAP1 protein affects the reaction [Oleanolic Acid inhibits the reaction [ochratoxin A results in increased expression of BAX protein]] | PMID:31401087 PMID:33465424 PMID:37345903 | |
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