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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620670
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Dcx
Name: doublecortin
Acc ID: CHEBI:3756
Term: clonazepam
Definition: 1,3-Dihydro-2H-1,4-benzodiazepin-2-one in which the hydrogens at positions 5 and 7 are substituted by 2-chlorophenyl and nitro groups, respectively. It is used in the treatment of all types of epilepsy and seizures, as well as myoclonus and associated abnormal movements, and panic disorders. However, its use can be limited by the development of tolerance and by sedation.
Chemical ID: MESH:D002998
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dcxdecreases expressionEXP 6480464CTDClonazepam results in decreased expression of DCX protein

PMID:19437554
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