GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | S1pr2 | increases activity | EXP | | 6480464 | CTD | sphingosine 1-phosphate results in increased activity of S1PR2 protein | PMID:22406263 | S1pr2 | multiple interactions | EXP | | 6480464 | CTD | [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein] [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [sphingosine 1-phosphate results in increased expression of FN1 protein] [JTE 013 binds to and results in decreased activity of S1PR2 protein] results in decreased susceptibility to [sphingosine 1-phosphate co-treated with Glucose] [JTE 013 binds to and results in decreased activity of S1PR2 protein] which results in decreased susceptibility to sphingosine 1-phosphate [sphingosine 1-phosphate results in increased activity of S1PR2 protein] which results in increased expression of FN1 | PMID:22406263 | S1pr2 | increases uptake | ISO | RGD:1343937 | 6480464 | CTD | sphingosine 1-phosphate results in increased uptake of S1PR2 protein | PMID:26518876 | S1pr2 | multiple interactions | ISO | RGD:1343937 | 6480464 | CTD | S1PR2 mutant form inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] | PMID:18612546 | | ||||||||||||||||||||||
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