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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621316
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp2
Name: matrix metallopeptidase 2
Acc ID: CHEBI:37550
Term: sphingosine 1-phosphate
Definition: A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1
Chemical ID: MESH:C060506
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp2increases expressionISORGD:7308216480464CTDsphingosine 1-phosphate results in increased expression of MMP2 mRNA sphingosine 1-phosphate results in increased expression of MMP2 protein

PMID:26518876
Mmp2multiple interactionsISORGD:7308216480464CTDJTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of MMP2 mRNA] JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of MMP2 protein]

PMID:26518876
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