GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ptgs2 | increases expression | ISO | RGD:731006 | 6480464 | CTD | sphingosine 1-phosphate results in increased expression of PTGS2 mRNA sphingosine 1-phosphate results in increased expression of PTGS2 protein | PMID:18612546 PMID:26518876 | Ptgs2 | multiple interactions | ISO | RGD:731006 | 6480464 | CTD | dihydrosphingosine 1-phosphate inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] dihydrosphingosine 1-phosphate inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein] JTE 013 inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]] JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein] JTE 013 promotes the reaction [Suramin inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]] Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]] MK 2206 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein] S1PR2 mutant form inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] S1PR3 mutant form inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] sphingosine 1-phosphate inhibits the reaction [dihydrosphingosine 1-phosphate results in increased expression of PTGS2 mRNA] sphingosine 1-phosphate inhibits the reaction [dihydrosphingosine 1-phosphate results in increased expression of PTGS2 protein] sphingosine 1-phosphate inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] sphingosine 1-phosphate inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 protein] Suramin inhibits the reaction [Simvastatin promotes the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]] Suramin inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA] Suramin promotes the reaction [JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of PTGS2 mRNA]] | PMID:18612546 PMID:26518876 | | ||||||||||||||||||||||
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