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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61958
Species: Rattus norvegicus
RGD Object: Gene
Symbol: S1pr1
Name: sphingosine-1-phosphate receptor 1
Acc ID: CHEBI:37550
Term: sphingosine 1-phosphate
Definition: A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1
Chemical ID: MESH:C060506
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
S1pr1increases response to substanceEXP 6480464CTDS1PR1 protein results in increased susceptibility to sphingosine 1-phosphate

PMID:20844107
S1pr1multiple interactionsEXP 6480464CTDsphingosine 1-phosphate binds to and results in increased activity of S1PR1 protein

PMID:20844107
S1pr1increases expressionISORGD:13461656480464CTDsphingosine 1-phosphate results in increased expression of S1PR1 mRNA

PMID:24399507
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