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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2624
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fn1
Name: fibronectin 1
Acc ID: CHEBI:37550
Term: sphingosine 1-phosphate
Definition: A phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1
Chemical ID: MESH:C060506
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fn1increases expressionEXP 6480464CTDsphingosine 1-phosphate results in increased expression of FN1 protein

PMID:21998146 PMID:22406263
Fn1multiple interactionsEXP 6480464CTD2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein] [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein] [JTE 013 binds to and results in decreased activity of S1PR2 protein] inhibits the reaction [sphingosine 1-phosphate results in increased expression of FN1 protein] [sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein [sphingosine 1-phosphate results in increased activity of S1PR2 protein] which results in increased expression of FN1 Curcumin inhibits the reaction [sphingosine 1-phosphate results in increased expression of FN1 protein] SB 203580 inhibits the reaction [[sphingosine 1-phosphate co-treated with Glucose] results in increased expression of FN1 protein]

PMID:21998146 PMID:22406263
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