GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cat | increases expression | EXP | | 6480464 | CTD | Clofibrate results in increased expression of CAT mRNA | PMID:17585979 | Cat | multiple interactions | EXP | | 6480464 | CTD | [Clofibrate co-treated with Acetaminophen] affects the expression of CAT mRNA; Clofibrate inhibits the reaction [[Fatty Acids, Nonesterified binds to ALB protein] which results in decreased expression of CAT protein]; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CAT mRNA] | PMID:17585979 PMID:21338618 | Cat | decreases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Clofibrate results in decreased activity of CAT protein | PMID:10528994 | Cat | increases activity | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Clofibrate results in increased activity of CAT protein | PMID:15200495 PMID:15212807 PMID:2260096 PMID:2399535 PMID:3625448 PMID:7192109 PMID:8250967 | Cat | increases expression | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Clofibrate results in increased expression of CAT mRNA; Clofibrate results in increased expression of CAT protein | PMID:1280124 PMID:16470657 PMID:1740018 PMID:18670166 PMID:2306265 PMID:6845354 PMID:9806150 | Cat | multiple interactions | ISO | Cat (Rattus norvegicus) | 6480464 | CTD | Cycloheximide inhibits the reaction [Clofibrate results in increased expression of CAT protein]; Dietary Fats promotes the reaction [Clofibrate results in increased activity of CAT protein]; Selenium affects the reaction [Clofibrate results in increased activity of CAT protein] | PMID:15200495 PMID:6845354 PMID:8250967 | | ||||||||||||||||||||||
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