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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733990
Species: Homo sapiens
RGD Object: Gene
Symbol: ACAA2
Name: acetyl-CoA acyltransferase 2
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ACAA2increases expressionISOAcaa2 (Mus musculus)6480464CTDClofibrate results in increased expression of ACAA2 mRNA; Clofibrate results in increased expression of ACAA2 proteinPMID:17585979 PMID:21338618
ACAA2increases expressionISOAcaa2 (Rattus norvegicus)6480464CTDClofibrate results in increased expression of ACAA2 mRNA; Clofibrate results in increased expression of ACAA2 proteinPMID:12011481 PMID:16470657 PMID:18670166 PMID:27665778 PMID:32741897 PMID:33983380
ACAA2multiple interactionsISOAcaa2 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of ACAA2 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ACAA2 mRNA]PMID:17585979
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