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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708367
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsd17b12
Name: hydroxysteroid (17-beta) dehydrogenase 12
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsd17b12increases expressionISOHsd17b12 (Mus musculus)6480464CTDClofibrate results in increased expression of HSD17B12 mRNAPMID:17585979
Hsd17b12multiple interactionsISOHsd17b12 (Mus musculus)6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of HSD17B12 mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HSD17B12 mRNA]PMID:17585979
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