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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620298
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcg5
Name: ATP binding cassette subfamily G member 5
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcg5affects expressionEXP 6480464CTDClofibrate affects the expression of ABCG5 mRNAPMID:19483382
Abcg5decreases expressionEXP 6480464CTDClofibrate results in decreased expression of ABCG5 mRNAPMID:12851107
Abcg5decreases expressionISOAbcg5 (Mus musculus)6480464CTDClofibrate results in decreased expression of ABCG5 mRNAPMID:28973556
Abcg5increases expressionISOAbcg5 (Mus musculus)6480464CTDClofibrate results in increased expression of ABCG5 mRNAPMID:22496397
Abcg5multiple interactionsISOAbcg5 (Mus musculus)6480464CTDClofibrate inhibits the reaction [PPARA gene mutant form results in increased expression of ABCG5 mRNA]PMID:29175453
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