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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1550861
Species: Mus musculus
RGD Object: Gene
Symbol: Plg
Name: plasminogen
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Plgdecreases expressionEXP 6480464CTDClofibrate results in decreased expression of PLG mRNAPMID:17585979
Plgmultiple interactionsEXP 6480464CTD[Clofibrate co-treated with Acetaminophen] affects the expression of PLG mRNA; PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of PLG mRNA]PMID:17585979
Plgaffects expressionISOPLG (Homo sapiens)6480464CTDClofibrate affects the expression of PLG proteinPMID:131008
Plgaffects expressionISOPlg (Rattus norvegicus)6480464CTDClofibrate affects the expression of PLG mRNAPMID:19483382
Plgdecreases expressionISOPlg (Rattus norvegicus)6480464CTDClofibrate results in decreased expression of PLG mRNAPMID:12851107
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