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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10864
Species: Mus musculus
RGD Object: Gene
Symbol: Ldlr
Name: low density lipoprotein receptor
Acc ID: CHEBI:3750
Term: clofibrate
Definition: The ethyl ester of clofibric acid.
Chemical ID: MESH:D002994
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ldlrdecreases expressionISOLdlr (Rattus norvegicus)6480464CTDClofibrate results in decreased expression of LDLR mRNAPMID:17126302
Ldlrmultiple interactionsISOLdlr (Rattus norvegicus)6480464CTD[Clofibrate co-treated with Diethylhexyl Phthalate] results in increased expression of LDLR mRNAPMID:9207284
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